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FUS and TDP-43 Phases in Health and Disease
The distinct prion-like domains (PrLDs) of FUS and TDP-43, modulate phase transitions that result in condensates with a range of material states. These assemblies are implicated in both health and disease. In this review, we examine how sequence, structure, post-translational modifications, and RNA...
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| Publicat a: | Trends Biochem Sci |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8195841/ https://ncbi.nlm.nih.gov/pubmed/33446423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2020.12.005 |
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