Human autologous iPSC–derived dopaminergic progenitors restore motor function in Parkinson’s disease models

Parkinson’s disease (PD) is a neurodegenerative disorder associated with loss of striatal dopamine, secondary to degeneration of midbrain dopamine (mDA) neurons in the substantia nigra, rendering cell transplantation a promising therapeutic strategy. To establish human induced pluripotent stem cell–...

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Udgivet i:J Clin Invest
Main Authors: Song, Bin, Cha, Young, Ko, Sanghyeok, Jeon, Jeha, Lee, Nayeon, Seo, Hyemyung, Park, Kyung-Joon, Lee, In-Hee, Lopes, Claudia, Feitosa, Melissa, Luna, María José, Jung, Jin Hyuk, Kim, Jisun, Hwang, Dabin, Cohen, Bruce M., Teicher, Martin H., Leblanc, Pierre, Carter, Bob S., Kordower, Jeffrey H., Bolshakov, Vadim Y., Kong, Sek Won, Schweitzer, Jeffrey S., Kim, Kwang-Soo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994130/
https://ncbi.nlm.nih.gov/pubmed/31714896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130767
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