Human autologous iPSC–derived dopaminergic progenitors restore motor function in Parkinson’s disease models

Parkinson’s disease (PD) is a neurodegenerative disorder associated with loss of striatal dopamine, secondary to degeneration of midbrain dopamine (mDA) neurons in the substantia nigra, rendering cell transplantation a promising therapeutic strategy. To establish human induced pluripotent stem cell–...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Song, Bin, Cha, Young, Ko, Sanghyeok, Jeon, Jeha, Lee, Nayeon, Seo, Hyemyung, Park, Kyung-Joon, Lee, In-Hee, Lopes, Claudia, Feitosa, Melissa, Luna, María José, Jung, Jin Hyuk, Kim, Jisun, Hwang, Dabin, Cohen, Bruce M., Teicher, Martin H., Leblanc, Pierre, Carter, Bob S., Kordower, Jeffrey H., Bolshakov, Vadim Y., Kong, Sek Won, Schweitzer, Jeffrey S., Kim, Kwang-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994130/
https://ncbi.nlm.nih.gov/pubmed/31714896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130767
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