Detailed Analysis of the Genetic and Epigenetic Signatures of iPSC-Derived Mesodiencephalic Dopaminergic Neurons

Induced pluripotent stem cells (iPSCs) hold great promise for in vitro generation of disease-relevant cell types, such as mesodiencephalic dopaminergic (mdDA) neurons involved in Parkinson’s disease. Although iPSC-derived midbrain DA neurons have been generated, detailed genetic and epigenetic chara...

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Autors principals: Reinhard Roessler, Sebastien A. Smallwood, Jesse V. Veenvliet, Petros Pechlivanoglou, Su-Ping Peng, Koushik Chakrabarty, Marian J.A. Groot-Koerkamp, R. Jeroen Pasterkamp, Evelyn Wesseling, Gavin Kelsey, Erik Boddeke, Marten P. Smidt, Sjef Copray
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2014-04-01
Col·lecció:Stem Cell Reports
Accés en línia:http://www.sciencedirect.com/science/article/pii/S2213671114000800
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