Detailed Analysis of the Genetic and Epigenetic Signatures of iPSC-Derived Mesodiencephalic Dopaminergic Neurons

Induced pluripotent stem cells (iPSCs) hold great promise for in vitro generation of disease-relevant cell types, such as mesodiencephalic dopaminergic (mdDA) neurons involved in Parkinson’s disease. Although iPSC-derived midbrain DA neurons have been generated, detailed genetic and epigenetic chara...

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主要な著者: Roessler, Reinhard, Smallwood, Sebastien A., Veenvliet, Jesse V., Pechlivanoglou, Petros, Peng, Su-Ping, Chakrabarty, Koushik, Groot-Koerkamp, Marian J.A., Pasterkamp, R. Jeroen, Wesseling, Evelyn, Kelsey, Gavin, Boddeke, Erik, Smidt, Marten P., Copray, Sjef
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2014
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986662/
https://ncbi.nlm.nih.gov/pubmed/24749075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.03.001
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