In vivo delivery of synthetic DNA–encoded antibodies induces broad HIV-1–neutralizing activity

Interventions to prevent HIV-1 infection and alternative tools in HIV cure therapy remain pressing goals. Recently, numerous broadly neutralizing HIV-1 monoclonal antibodies (bNAbs) have been developed that possess the characteristics necessary for potential prophylactic or therapeutic approaches. H...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Wise, Megan C., Xu, Ziyang, Tello-Ruiz, Edgar, Beck, Charles, Trautz, Aspen, Patel, Ami, Elliott, Sarah T.C., Chokkalingam, Neethu, Kim, Sophie, Kerkau, Melissa G., Muthumani, Kar, Jiang, Jingjing, Fisher, Paul D., Ramos, Stephany J., Smith, Trevor R.F., Mendoza, Janess, Broderick, Kate E., Montefiori, David C., Ferrari, Guido, Kulp, Daniel W., Humeau, Laurent M., Weiner, David B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994112/
https://ncbi.nlm.nih.gov/pubmed/31697648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI132779
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