Characterization and Optimization of Multiplexed Quantitative Analyses Using High-Field Asymmetric-Waveform Ion Mobility Mass Spectrometry

Multiplexed, isobaric tagging methods are powerful techniques to increase throughput, precision, and accuracy in quantitative proteomics. The dynamic range and accuracy of quantitation, however, can be limited by coisolation of tag-containing peptides that release reporter ions and conflate quantita...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Schweppe, Devin K., Prasad, Satendra, Belford, Michael W., Navarrete-Perea, José, Bailey, Derek J., Huguet, Romain, Jedrychowski, Mark P., Rad, Ramin, McAlister, Graeme, Abbatiello, Susan E., Woulters, Eloy R., Zabrouskov, Vlad, Dunyach, Jean-Jacques, Paulo, João A., Gygi, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993951/
https://ncbi.nlm.nih.gov/pubmed/30672687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b05399
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