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Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis
Melatonin, a neuroendocrine hormone synthesized by the pineal gland and cholangiocytes, decreases biliary hyperplasia and liver fibrosis during cholestasis-induced biliary injury via melatonin-dependent autocrine signaling through increased biliary arylalkylamine N-acetyltransferase (AANAT) expressi...
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| Yayımlandı: | Biochim Biophys Acta Mol Basis Dis |
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| Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6993622/ https://ncbi.nlm.nih.gov/pubmed/30890428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2019.03.002 |
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