Downregulation of p16 Decreases Biliary Damage and Liver Fibrosis in the Mdr2(−/−) Mouse Model of Primary Sclerosing Cholangitis

Biliary senescence and hepatic fibrosis are hallmarks of cholangiopathies including primary sclerosing cholangitis (PSC). Senescent cholangiocytes display senescence-associated secretory phenotypes [SASPs, e.g., transforming growth factor-β1 (TGF-β1)] that further increase biliary senescence (by an...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Gene Expr
Main Authors: Kyritsi, Konstantina, Francis, Heather, Zhou, Tianhao, Ceci, Ludovica, Wu, Nan, Yang, Zhihong, Meng, Fanyin, Chen, Lixian, Baiocchi, Leonardo, Kundu, Debjyoti, Kennedy, Lindsey, Liangpunsakul, Suthat, Wu, Chaodong, Glaser, Shannon, Alpini, Gianfranco
Formato: Artigo
Idioma:Inglês
Publicado em: Cognizant Communication Corporation 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650011/
https://ncbi.nlm.nih.gov/pubmed/32393417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/105221620X15889714507961
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados