Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2(−/−) mouse model of primary sclerosing cholangitis (PSC)

BACKGROUND: Cholangiocytes are the target cells of cholangiopathies including primary sclerosing cholangitis (PSC). Vimentin is an intermediate filament protein that has been found in various types of mesenchymal cells. The aim of this study is to evaluate the role of vimentin in the progression of...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Zhou, Tianhao, Kyritsi, Konstantina, Wu, Nan, Francis, Heather, Yang, Zhihong, Chen, Lixian, O'Brien, April, Kennedy, Lindsey, Ceci, Ludovica, Meadows, Vik, Kusumanchi, Praveen, Wu, Chaodong, Baiocchi, Leonardo, Skill, Nicholas J., Saxena, Romil, Sybenga, Amelia, Xie, Linglin, Liangpunsakul, Suthat, Meng, Fanyin, Alpini, Gianfranco, Glaser, Shannon
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838376/
https://ncbi.nlm.nih.gov/pubmed/31522982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.013
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