Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2(−/−) mouse model of primary sclerosing cholangitis (PSC)

BACKGROUND: Cholangiocytes are the target cells of cholangiopathies including primary sclerosing cholangitis (PSC). Vimentin is an intermediate filament protein that has been found in various types of mesenchymal cells. The aim of this study is to evaluate the role of vimentin in the progression of...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:EBioMedicine
Auteurs principaux: Zhou, Tianhao, Kyritsi, Konstantina, Wu, Nan, Francis, Heather, Yang, Zhihong, Chen, Lixian, O'Brien, April, Kennedy, Lindsey, Ceci, Ludovica, Meadows, Vik, Kusumanchi, Praveen, Wu, Chaodong, Baiocchi, Leonardo, Skill, Nicholas J., Saxena, Romil, Sybenga, Amelia, Xie, Linglin, Liangpunsakul, Suthat, Meng, Fanyin, Alpini, Gianfranco, Glaser, Shannon
Format: Artigo
Langue:Inglês
Publié: Elsevier 2019
Sujets:
Research paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838376/
https://ncbi.nlm.nih.gov/pubmed/31522982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.013
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires