Identification of the leptin receptor sequences crucial for the STAT3-Independent control of metabolism

BACKGROUND: Leptin acts via its receptor, LepRb, on specialized neurons in the brain to modulate energy balance and glucose homeostasis. LepRb→STAT3 signaling plays a crucial role in leptin action, but LepRb also mediates an additional as-yet-unidentified signal (Signal 2) that is important for lept...

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Veröffentlicht in:Mol Metab
Hauptverfasser: Barnes, Tammy M., Shah, Kimi, Allison, Margaret B., Steinl, Gabrielle K., Gordian, Desiree, Sabatini, Paul V., Tomlinson, Abigail J., Cheng, Wenwen, Jones, Justin C., Zhu, Qing, Faber, Chelsea, Myers, Martin G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992902/
https://ncbi.nlm.nih.gov/pubmed/32029227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.12.013
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