Transcriptional and physiological roles for STAT proteins in leptin action

OBJECTIVES: Leptin acts via its receptor LepRb on specialized neurons in the brain to modulate food intake, energy expenditure, and body weight. LepRb activates signal transducers and activators of transcription (STATs, including STAT1, STAT3, and STAT5) to control gene expression. METHODS: Because...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Pan, Warren, Allison, Margaret B., Sabatini, Paul, Rupp, Alan, Adams, Jessica, Patterson, Christa, Jones, Justin C., Olson, David P., Myers, Martin G.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437596/
https://ncbi.nlm.nih.gov/pubmed/30718218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.01.007
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