Identification of the leptin receptor sequences crucial for the STAT3-Independent control of metabolism

BACKGROUND: Leptin acts via its receptor, LepRb, on specialized neurons in the brain to modulate energy balance and glucose homeostasis. LepRb→STAT3 signaling plays a crucial role in leptin action, but LepRb also mediates an additional as-yet-unidentified signal (Signal 2) that is important for lept...

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Vydáno v:Mol Metab
Hlavní autoři: Barnes, Tammy M., Shah, Kimi, Allison, Margaret B., Steinl, Gabrielle K., Gordian, Desiree, Sabatini, Paul V., Tomlinson, Abigail J., Cheng, Wenwen, Jones, Justin C., Zhu, Qing, Faber, Chelsea, Myers, Martin G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992902/
https://ncbi.nlm.nih.gov/pubmed/32029227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.12.013
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