Appropriate Inhibition of Orexigenic Hypothalamic Arcuate Nucleus Neurons Independently of Leptin Receptor/STAT3 Signaling

Leptin directly suppresses the activity of orexigenic neurons in the hypothalamic arcuate nucleus (ARC). We examined c-Fos-like immunoreactivity (CFLIR) as a marker of ARC neuronal activity in db/db mice devoid of the signaling form of the leptin receptor (LRb) and s/s mice that express LRb(S1138) [...

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Gepubliceerd in:J Neurosci
Hoofdauteurs: Münzberg, Heike, Jobst, Erin E., Bates, Sarah H., Jones, Justin, Villanueva, Eneida, Leshan, Rebecca, Björnholm, Marie, Elmquist, Joel, Sleeman, Mark, Cowley, Michael A., Myers, Martin G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672286/
https://ncbi.nlm.nih.gov/pubmed/17202473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3168-06.2007
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