Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function

The adipose-derived hormone, leptin, acts via its receptor (LRb) to convey the status of body energy stores to the brain, decreasing feeding and potentiating neuroendocrine energy expenditure. The failure of high levels of leptin in most obese individuals to promote weight loss defines a state of di...

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Detalhes bibliográficos
Main Authors: Björnholm, Marie, Münzberg, Heike, Leshan, Rebecca L., Villanueva, Eneida C., Bates, Sarah H., Louis, Gwendolyn W., Jones, Justin C., Ishida-Takahashi, Ryoko, Bjørbaek, Christian, Myers, Martin G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838925/
https://ncbi.nlm.nih.gov/pubmed/17415414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30688
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