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Ablation of the Leptin Receptor in the Hypothalamic Arcuate Nucleus Abrogates Leptin-Induced Sympathetic Activation

RATIONALE: The hypothalamic arcuate nucleus (ARC) is considered as a major site for leptin signaling that regulates several physiological processes. OBJECTIVE: To test the hypothesis that leptin receptor in the ARC is required to mediate leptin-induced sympathetic activation. METHODS AND RESULTS: Fi...

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Detalhes bibliográficos
Main Authors: Harlan, Shannon M., Morgan, Donald A., Agassandian, Khristofor, Guo, Deng-Fu, Cassell, Martin D., Sigmund, Curt D., Mark, Allyn L., Rahmouni, Kamal
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072835/
https://ncbi.nlm.nih.gov/pubmed/21311043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.240226
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