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LEPTIN SIGNALING IN THE NUCLEUS TRACTUS SOLITARII INCREASES SYMPATHETIC NERVE ACTIVITY TO THE KIDNEY

The hypothalamic arcuate nucleus was initially regarded as the principal site of leptin action, but there is increasing evidence for functional leptin receptors (Ob-Rb) in extra-hypothalamic sites, including the nucleus tractus solitarii (NTS). We previously demonstrated that arcuate injection of le...

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Detalhes bibliográficos
Main Authors: Mark, Allyn L., Agassandian, Khristofor, Morgan, Donald A., Liu, Xuebo, Cassell, Martin D, Rahmouni, Kamal
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688398/
https://ncbi.nlm.nih.gov/pubmed/19103999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.108.124255
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