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LEPTIN SIGNALING IN THE NUCLEUS TRACTUS SOLITARII INCREASES SYMPATHETIC NERVE ACTIVITY TO THE KIDNEY

The hypothalamic arcuate nucleus was initially regarded as the principal site of leptin action, but there is increasing evidence for functional leptin receptors (Ob-Rb) in extra-hypothalamic sites, including the nucleus tractus solitarii (NTS). We previously demonstrated that arcuate injection of le...

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Main Authors: Mark, Allyn L., Agassandian, Khristofor, Morgan, Donald A., Liu, Xuebo, Cassell, Martin D, Rahmouni, Kamal
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688398/
https://ncbi.nlm.nih.gov/pubmed/19103999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.108.124255
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