Specific subpopulations of hypothalamic leptin receptor-expressing neurons mediate the effects of early developmental leptin receptor deletion on energy balance

OBJECTIVE: To date, early developmental ablation of leptin receptor (LepRb) expression from circumscribed populations of hypothalamic neurons (e.g., arcuate nucleus (ARC) Pomc- or Agrp-expressing cells) has only minimally affected energy balance. In contrast, removal of LepRb from at least two large...

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Publicado no:Mol Metab
Main Authors: Rupp, Alan C., Allison, Margaret B., Jones, Justin C., Patterson, Christa M., Faber, Chelsea L., Bozadjieva, Nadejda, Heisler, Lora K., Seeley, Randy J., Olson, David P., Myers, Martin G.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6034096/
https://ncbi.nlm.nih.gov/pubmed/29914853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.06.001
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