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Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding

The lateral hypothalamic area (LHA) acts in concert with the ventral tegmental area (VTA) and other components of the mesolimbic dopamine (DA) system to control motivation, including the incentive to feed. The anorexigenic hormone, leptin, modulates the mesolimbic DA system, although the mechanisms...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Leinninger, Gina M., Jo, Young-Hwan, Leshan, Rebecca L., Louis, Gwendolyn W., Yang, Hongyan, Barrera, Jason G., Wilson, Hilary, Opland, Darren M., Faouzi, Miro A., Gong, Yusong, Jones, Justin C., Rhodes, Christopher J., Chua, Streamson, Diano, Sabrina, Horvath, Tamas L., Seeley, Randy J., Becker, Jill B., Münzberg, Heike, Myers, Martin G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723060/
https://ncbi.nlm.nih.gov/pubmed/19656487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.06.011
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