Transcriptional and physiological roles for STAT proteins in leptin action

OBJECTIVES: Leptin acts via its receptor LepRb on specialized neurons in the brain to modulate food intake, energy expenditure, and body weight. LepRb activates signal transducers and activators of transcription (STATs, including STAT1, STAT3, and STAT5) to control gene expression. METHODS: Because...

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Gepubliceerd in:Mol Metab
Hoofdauteurs: Pan, Warren, Allison, Margaret B., Sabatini, Paul, Rupp, Alan, Adams, Jessica, Patterson, Christa, Jones, Justin C., Olson, David P., Myers, Martin G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2019
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437596/
https://ncbi.nlm.nih.gov/pubmed/30718218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.01.007
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