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ATM, ATR and DNA-PKcs kinases—the lessons from the mouse models: inhibition ≠ deletion
DNA damage, especially DNA double strand breaks (DSBs) and replication stress, activates a complex post-translational network termed DNA damage response (DDR). Our review focuses on three PI3-kinase related protein kinases—ATM, ATR and DNA-PKcs, which situate at the apex of the mammalian DDR. They a...
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| Udgivet i: | Cell Biosci |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6990542/ https://ncbi.nlm.nih.gov/pubmed/32015826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-020-0376-x |
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