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Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells
The cellular response to DNA double-strand breaks involves direct activation of ataxia telangiectasia mutated (ATM) and indirect activation of ataxia telangiectasia and Rad3 related (ATR) in an ATM/Mre11/cell-cycle-dependent manner. Here, we report that the crucial checkpoint signalling proteins—p53...
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| Päätekijät: | , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711839/ https://ncbi.nlm.nih.gov/pubmed/19444312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.60 |
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