Rapid Characterization of hERG Channel Kinetics II: Temperature Dependence

Ion channel behavior can depend strongly on temperature, with faster kinetics at physiological temperatures leading to considerable changes in currents relative to room temperature. These temperature-dependent changes in voltage-dependent ion channel kinetics (rates of opening, closing, inactivating...

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Publicat a:Biophys J
Autors principals: Lei, Chon Lok, Clerx, Michael, Beattie, Kylie A., Melgari, Dario, Hancox, Jules C., Gavaghan, David J., Polonchuk, Liudmila, Wang, Ken, Mirams, Gary R.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2019
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990152/
https://ncbi.nlm.nih.gov/pubmed/31451180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.030
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