Suppression of the hERG potassium channel response to premature stimulation by reduction in extracellular potassium concentration

Potassium channels encoded by human ether‐à‐go‐go‐related gene (hERG) mediate the cardiac rapid delayed rectifier K(+) current (I(Kr)), which participates in ventricular repolarization and has a protective role against unwanted premature stimuli late in repolarization and early in diastole. Ionic cu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Physiol Rep
Prif Awduron: Melgari, Dario, Du, Chunyun, El Harchi, Aziza, Zhang, Yihong, Hancox, Jules C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Wiley Periodicals, Inc. 2014
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254092/
https://ncbi.nlm.nih.gov/pubmed/25318749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12165
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