Suppression of the hERG potassium channel response to premature stimulation by reduction in extracellular potassium concentration

Potassium channels encoded by human ether‐à‐go‐go‐related gene (hERG) mediate the cardiac rapid delayed rectifier K(+) current (I(Kr)), which participates in ventricular repolarization and has a protective role against unwanted premature stimuli late in repolarization and early in diastole. Ionic cu...

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Bibliografiske detaljer
Udgivet i:Physiol Rep
Main Authors: Melgari, Dario, Du, Chunyun, El Harchi, Aziza, Zhang, Yihong, Hancox, Jules C.
Format: Artigo
Sprog:Inglês
Udgivet: Wiley Periodicals, Inc. 2014
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254092/
https://ncbi.nlm.nih.gov/pubmed/25318749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12165
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