Suppression of the hERG potassium channel response to premature stimulation by reduction in extracellular potassium concentration

Potassium channels encoded by human ether‐à‐go‐go‐related gene (hERG) mediate the cardiac rapid delayed rectifier K(+) current (I(Kr)), which participates in ventricular repolarization and has a protective role against unwanted premature stimuli late in repolarization and early in diastole. Ionic cu...

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Bibliographic Details
Published in:Physiol Rep
Main Authors: Melgari, Dario, Du, Chunyun, El Harchi, Aziza, Zhang, Yihong, Hancox, Jules C.
Format: Artigo
Language:Inglês
Published: Wiley Periodicals, Inc. 2014
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254092/
https://ncbi.nlm.nih.gov/pubmed/25318749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12165
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