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Modification by KCNE1 variants of the hERG potassium channel response to premature stimulation and to pharmacological inhibition
human Ether-à-go-go-Related Gene (hERG) encodes the pore-forming subunit of cardiac rapid delayed rectifier K(+) current (I(Kr)) channels, which play important roles in ventricular repolarization, in protecting the myocardium from unwanted premature stimuli, and in drug-induced Long QT Syndrome (LQT...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3871485/ https://ncbi.nlm.nih.gov/pubmed/24400172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phy2.175 |
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