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Expression of human lambda expands the repertoire of OmniChickens

Most of the approved monoclonal antibodies used in the clinic were initially discovered in mice. However, many targets of therapeutic interest are highly conserved proteins that do not elicit a robust immune response in mice. There is a need for non-mammalian antibody discovery platforms which would...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Ching, Kathryn H., Berg, Kimberley, Morales, Jacqueline, Pedersen, Darlene, Harriman, William D., Abdiche, Yasmina N., Leighton, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988971/
https://ncbi.nlm.nih.gov/pubmed/31995598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228164
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