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Expression of human lambda expands the repertoire of OmniChickens

Most of the approved monoclonal antibodies used in the clinic were initially discovered in mice. However, many targets of therapeutic interest are highly conserved proteins that do not elicit a robust immune response in mice. There is a need for non-mammalian antibody discovery platforms which would...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Ching, Kathryn H., Berg, Kimberley, Morales, Jacqueline, Pedersen, Darlene, Harriman, William D., Abdiche, Yasmina N., Leighton, Philip A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988971/
https://ncbi.nlm.nih.gov/pubmed/31995598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228164
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