Identification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase Cθ (PKCθ)

PKC (protein kinase C) θ is predominantly expressed in T-cells and is critically involved in immunity. Design of PKCθ-selective molecules to manage autoimmune disorders by targeting its activator-binding C1 domain requires the knowledge of its structure and the activator-binding residues. The C1 dom...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Biochem J
Autori principali: Rahman, Ghazi M., Shanker, Sreejesh, Lewin, Nancy E., Kedei, Noemi, Hill, Colin S., Prasad, B. V. Venkataram, Blumberg, Peter M., Das, Joydip
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988732/
https://ncbi.nlm.nih.gov/pubmed/23289588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20121307
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi