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Somatostatin secretion by Na(+)-dependent Ca(2+)-induced Ca(2+) release in pancreatic delta-cells
Pancreatic islets are complex micro-organs consisting of at least three different cell types: glucagon-secreting α-, insulin-producing β- and somatostatin-releasing δ-cells(1). Somatostatin is a powerful paracrine inhibitor of insulin and glucagon secretion(2). In diabetes, increased somatostatinerg...
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| Udgivet i: | Nat Metab |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6986923/ https://ncbi.nlm.nih.gov/pubmed/31993555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-019-0158-0 |
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