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GLI transcriptional repression regulates tissue-specific enhancer activity in response to Hedgehog signaling
Transcriptional repression needs to be rapidly reversible during embryonic development. This extends to the Hedgehog pathway, which primarily serves to counter GLI repression by processing GLI proteins into transcriptional activators. In investigating the mechanisms underlying GLI repression, we fin...
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| Publié dans: | eLife |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6986877/ https://ncbi.nlm.nih.gov/pubmed/31989924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50670 |
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