Spatiotemporal regulation of GLI target genes in the mammalian limb bud

GLI proteins convert Sonic hedgehog (Shh) signaling into a transcriptional output in a tissue-specific fashion. The Shh pathway has been extensively studied in the limb bud, where it helps regulate growth through a SHH-FGF feedback loop. However, the transcriptional response is still poorly understo...

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Enregistré dans:
Détails bibliographiques
Publié dans:Dev Biol
Auteurs principaux: Lewandowski, Jordan P., Du, Fang, Zhang, Shilu, Powell, Marian B., Falkenstein, Kristin N., Ji, Hongkai, Vokes, Steven A.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587286/
https://ncbi.nlm.nih.gov/pubmed/26238476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.07.022
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