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A Gli silencer is required for robust repression of gremlin in the vertebrate limb bud
The transcriptional response to the Hedgehog (Hh) pathway is mediated by Gli proteins, which function as context-dependent transcriptional activators or repressors. However, the mechanism by which Gli proteins regulate their target genes is poorly understood. Here, we have performed the first geneti...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3994773/ https://ncbi.nlm.nih.gov/pubmed/24700818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.104299 |
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