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A Gli silencer is required for robust repression of gremlin in the vertebrate limb bud

The transcriptional response to the Hedgehog (Hh) pathway is mediated by Gli proteins, which function as context-dependent transcriptional activators or repressors. However, the mechanism by which Gli proteins regulate their target genes is poorly understood. Here, we have performed the first geneti...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Li, Qiang, Lewandowski, Jordan P., Powell, Marian B., Norrie, Jacqueline L., Cho, Seung Hee, Vokes, Steven A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994773/
https://ncbi.nlm.nih.gov/pubmed/24700818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.104299
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