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A Gli silencer is required for robust repression of gremlin in the vertebrate limb bud

The transcriptional response to the Hedgehog (Hh) pathway is mediated by Gli proteins, which function as context-dependent transcriptional activators or repressors. However, the mechanism by which Gli proteins regulate their target genes is poorly understood. Here, we have performed the first geneti...

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書誌詳細
主要な著者: Li, Qiang, Lewandowski, Jordan P., Powell, Marian B., Norrie, Jacqueline L., Cho, Seung Hee, Vokes, Steven A.
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994773/
https://ncbi.nlm.nih.gov/pubmed/24700818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.104299
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