MicroRNA-mediated downregulation of K(+) channels in pulmonary arterial hypertension

Downregulated expression of K(+) channels and decreased K(+) currents in pulmonary artery smooth muscle cells (PASMC) have been implicated in the development of sustained pulmonary vasoconstriction and vascular remodeling in patients with idiopathic pulmonary arterial hypertension (IPAH). However, i...

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Vydáno v:Am J Physiol Lung Cell Mol Physiol
Hlavní autoři: Babicheva, Aleksandra, Ayon, Ramon J., Zhao, Tengteng, Ek Vitorin, Jose F., Pohl, Nicole M., Yamamura, Aya, Yamamura, Hisao, Quinton, Brooke A., Ba, Manqing, Wu, Linda, Ravellette, Keeley S., Rahimi, Shamin, Balistrieri, Francesca, Harrington, Angela, Vanderpool, Rebecca R., Thistlethwaite, Patricia A., Makino, Ayako, Yuan, Jason X.-J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985878/
https://ncbi.nlm.nih.gov/pubmed/31553627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00010.2019
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