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Enhanced Ca(2+)-sensing Receptor Function in Idiopathic Pulmonary Arterial Hypertension
RATIONALE: A rise in cytosolic Ca(2+) concentration ([Ca(2+)](cyt)) in pulmonary arterial smooth muscle cells (PASMC) is an important stimulus for pulmonary vasoconstriction and vascular remodeling. Increased resting [Ca(2+)](cyt) and enhanced Ca(2+) influx have been implicated in PASMC from patient...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3695473/ https://ncbi.nlm.nih.gov/pubmed/22730443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.266361 |
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