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Dihydropyridine Ca(2+) Channel Blockers Increase Cytosolic [Ca(2+)] by Activating Ca(2+)-sensing Receptors in Pulmonary Arterial Smooth Muscle Cells
RATIONALE: An increase in cytosolic free Ca(2+) concentration ([Ca(2+)](cyt)) in pulmonary arterial smooth muscle cells (PASMC) is a major trigger for pulmonary vasoconstriction and an important stimulus for PASMC proliferation and pulmonary vascular remodeling. The dihydropyridine Ca(2+) channel bl...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3642037/ https://ncbi.nlm.nih.gov/pubmed/23300272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.113.300897 |
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