Dihydropyridine Ca(2+) Channel Blockers Increase Cytosolic [Ca(2+)] by Activating Ca(2+)-sensing Receptors in Pulmonary Arterial Smooth Muscle Cells

RATIONALE: An increase in cytosolic free Ca(2+) concentration ([Ca(2+)](cyt)) in pulmonary arterial smooth muscle cells (PASMC) is a major trigger for pulmonary vasoconstriction and an important stimulus for PASMC proliferation and pulmonary vascular remodeling. The dihydropyridine Ca(2+) channel bl...

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Detalhes bibliográficos
Main Authors: Yamamura, Aya, Yamamura, Hisao, Guo, Qiang, Zimnicka, Adriana M., Wan, Jun, Ko, Eun A., Smith, Kimberly A., Pohl, Nicole M., Song, Shanshan, Zeifman, Amy, Makino, Ayako, Yuan, Jason X.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642037/
https://ncbi.nlm.nih.gov/pubmed/23300272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.113.300897
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