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Flow shear stress enhances intracellular Ca(2+) signaling in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension
An increase in cytosolic Ca(2+) concentration ([Ca(2+)](cyt)) in pulmonary arterial smooth muscle cells (PASMC) is a major trigger for pulmonary vasoconstriction and an important stimulus for pulmonary arterial medial hypertrophy in patients with idiopathic pulmonary arterial hypertension (IPAH). Va...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Physiological Society
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4137136/ https://ncbi.nlm.nih.gov/pubmed/24920677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00115.2014 |
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