Flow shear stress enhances intracellular Ca(2+) signaling in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension

An increase in cytosolic Ca(2+) concentration ([Ca(2+)](cyt)) in pulmonary arterial smooth muscle cells (PASMC) is a major trigger for pulmonary vasoconstriction and an important stimulus for pulmonary arterial medial hypertrophy in patients with idiopathic pulmonary arterial hypertension (IPAH). Va...

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Bibliographische Detailangaben
Hauptverfasser: Song, Shanshan, Yamamura, Aya, Yamamura, Hisao, Ayon, Ramon J., Smith, Kimberly A., Tang, Haiyang, Makino, Ayako, Yuan, Jason X.-J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2014
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137136/
https://ncbi.nlm.nih.gov/pubmed/24920677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00115.2014
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