MicroRNA-mediated downregulation of K(+) channels in pulmonary arterial hypertension

Downregulated expression of K(+) channels and decreased K(+) currents in pulmonary artery smooth muscle cells (PASMC) have been implicated in the development of sustained pulmonary vasoconstriction and vascular remodeling in patients with idiopathic pulmonary arterial hypertension (IPAH). However, i...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Babicheva, Aleksandra, Ayon, Ramon J., Zhao, Tengteng, Ek Vitorin, Jose F., Pohl, Nicole M., Yamamura, Aya, Yamamura, Hisao, Quinton, Brooke A., Ba, Manqing, Wu, Linda, Ravellette, Keeley S., Rahimi, Shamin, Balistrieri, Francesca, Harrington, Angela, Vanderpool, Rebecca R., Thistlethwaite, Patricia A., Makino, Ayako, Yuan, Jason X.-J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985878/
https://ncbi.nlm.nih.gov/pubmed/31553627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00010.2019
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