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Attenuated pulmonary fibrosis in sialidase-3 knockout (Neu3(−/−)) mice

Pulmonary fibrosis involves the formation of inappropriate scar tissue in the lungs, but what drives fibrosis is unclear. Sialidases (also called neuraminidases) cleave terminal sialic acids from glycoconjugates. In humans and mice, pulmonary fibrosis is associated with desialylation of glycoconjuga...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Karhadkar, Tejas R., Chen, Wensheng, Gomer, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985870/
https://ncbi.nlm.nih.gov/pubmed/31617733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00275.2019
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