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High-Fat Diet–Induced Adipose Tissue and Liver Inflammation and Steatosis in Mice Are Reduced by Inhibiting Sialidases

High-fat diet (HFD)–induced inflammation and steatosis of adipose tissue and liver are associated with a variety of serious health risks. Sialic acids are found as the distal terminal sugar on glycoproteins, which are removed by sialidases (neuraminidases). In humans and mice, pulmonary fibrosis is...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Pilling, Darrell, Karhadkar, Tejas R., Gomer, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7786079/
https://ncbi.nlm.nih.gov/pubmed/33039353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2020.09.011
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