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Serum Amyloid P inhibits single stranded RNA-induced lung inflammation, lung damage, and cytokine storm in mice

SARS-CoV-2 is a single stranded RNA (ssRNA) virus and contains GU-rich sequences distributed abundantly in the genome. In COVID-19, the infection and immune hyperactivation causes accumulation of inflammatory immune cells, blood clots, and protein aggregates in lung fluid, increased lung alveolar wa...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Karhadkar, Tejas R., Pilling, Darrell, Gomer, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457621/
https://ncbi.nlm.nih.gov/pubmed/32869032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.08.26.269183
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