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Serum Amyloid P and a Dendritic Cell–Specific Intercellular Adhesion Molecule-3–Grabbing Nonintegrin Ligand Inhibit High-Fat Diet–Induced Adipose Tissue and Liver Inflammation and Steatosis in Mice

High-fat diet (HFD)–induced inflammation is associated with a variety of health risks. The systemic pentraxin serum amyloid P (SAP) inhibits inflammation. SAP activates the high-affinity IgG receptor Fcγ receptor I (FcγRI; CD64) and the lectin receptor dendritic cell–specific intercellular adhesion...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Pilling, Darrell, Cox, Nehemiah, Thomson, Megan A., Karhadkar, Tejas R., Gomer, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902115/
https://ncbi.nlm.nih.gov/pubmed/31539521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.08.005
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