Serum Amyloid P and a Dendritic Cell–Specific Intercellular Adhesion Molecule-3–Grabbing Nonintegrin Ligand Inhibit High-Fat Diet–Induced Adipose Tissue and Liver Inflammation and Steatosis in Mice

High-fat diet (HFD)–induced inflammation is associated with a variety of health risks. The systemic pentraxin serum amyloid P (SAP) inhibits inflammation. SAP activates the high-affinity IgG receptor Fcγ receptor I (FcγRI; CD64) and the lectin receptor dendritic cell–specific intercellular adhesion...

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Vydáno v:Am J Pathol
Hlavní autoři: Pilling, Darrell, Cox, Nehemiah, Thomson, Megan A., Karhadkar, Tejas R., Gomer, Richard H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902115/
https://ncbi.nlm.nih.gov/pubmed/31539521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.08.005
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