Elevated expression of NEU1 sialidase in idiopathic pulmonary fibrosis provokes pulmonary collagen deposition, lymphocytosis, and fibrosis

Idiopathic pulmonary fibrosis (IPF) poses challenges to understanding its underlying cellular and molecular mechanisms and the development of better therapies. Previous studies suggest a pathophysiological role for neuraminidase 1 (NEU1), an enzyme that removes terminal sialic acid from glycoprotein...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Luzina, Irina G., Lockatell, Virginia, Hyun, Sang W., Kopach, Pavel, Kang, Phillip H., Noor, Zahid, Liu, Anguo, Lillehoj, Erik P., Lee, Chunsik, Miranda-Ribera, Alba, Todd, Nevins W., Goldblum, Simeon E., Atamas, Sergei P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896097/
https://ncbi.nlm.nih.gov/pubmed/26993524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00346.2015
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