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Translational Approach to Predicting the Efficacy of Maraviroc-Based Regimens as HIV Preexposure Prophylaxis

Maraviroc-based regimens have been explored as preexposure prophylaxis (PrEP) against human immunodeficiency virus (HIV). In this study, we utilized mucosal tissue drug exposure data, combined with target concentrations generated in vitro, in a pharmacokinetic-pharmacodynamic analysis to predict the...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Antimicrob Agents Chemother
Main Authors: Srinivas, Nithya, Cottrell, Mackenzie, Maffuid, Kaitlyn, Prince, Heather A., Nelson, Julie A. E., White, Nicole, Sykes, Craig, Dellon, Evan S., Madanick, Ryan D., Shaheen, Nicholas J., Gonzalez, Daniel, Kashuba, Angela D. M.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985753/
https://ncbi.nlm.nih.gov/pubmed/31740561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01729-19
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