Translational Approach to Predicting the Efficacy of Maraviroc-Based Regimens as HIV Preexposure Prophylaxis

Maraviroc-based regimens have been explored as preexposure prophylaxis (PrEP) against human immunodeficiency virus (HIV). In this study, we utilized mucosal tissue drug exposure data, combined with target concentrations generated in vitro, in a pharmacokinetic-pharmacodynamic analysis to predict the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Srinivas, Nithya, Cottrell, Mackenzie, Maffuid, Kaitlyn, Prince, Heather A., Nelson, Julie A. E., White, Nicole, Sykes, Craig, Dellon, Evan S., Madanick, Ryan D., Shaheen, Nicholas J., Gonzalez, Daniel, Kashuba, Angela D. M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2020
Gaiak:
Pharmacology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985753/
https://ncbi.nlm.nih.gov/pubmed/31740561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01729-19
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