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Age-Dependent Decline in Cardiac Function in Guanidinoacetate-N-Methyltransferase Knockout Mice
AIM: Guanidinoacetate N-methyltransferase (GAMT) is the second essential enzyme in creatine (Cr) biosynthesis. Short-term Cr deficiency is metabolically well tolerated as GAMT(–/–) mice exhibit normal exercise capacity and response to ischemic heart failure. However, we hypothesized long-term conseq...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Front Physiol |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Frontiers Media S.A.
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6985570/ https://ncbi.nlm.nih.gov/pubmed/32038270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01535 |
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