Is rate–pressure product of any use in the isolated rat heart? Assessing cardiac ‘effort’ and oxygen consumption in the Langendorff‐perfused heart

Por Aksentijević, Dunja, Lewis, Hannah R., Shattock, Michael J.
Publicado no Exp Physiol (2016)

Multiple quantum filtered (23)Na NMR in the Langendorff perfused mouse heart: Ratio of triple/double quantum filtered signals correlates with [Na](i)

Por Eykyn, Thomas R., Aksentijević, Dunja, Aughton, Karen L., Southworth, Richard, Fuller, William, Shattock, Michael J.
Publicado no J Mol Cell Cardiol (2015)

Ribose Supplementation Alone or with Elevated Creatine Does Not Preserve High Energy Nucleotides or Cardiac Function in the Failing Mouse Heart

Por Faller, Kiterie M. E., Medway, Debra J., Aksentijevic, Dunja, Sebag-Montefiore, Liam, Schneider, Jürgen E., Lygate, Craig A., Neubauer, Stefan
Publicado em 2013

Myocardial Creatine Levels Do Not Influence Response to Acute Oxidative Stress in Isolated Perfused Heart

Por Aksentijević, Dunja, Zervou, Sevasti, Faller, Kiterie M. E., McAndrew, Debra J., Schneider, Jurgen E., Neubauer, Stefan, Lygate, Craig A.
Publicado em 2014

High-energy phosphotransfer in the failing mouse heart: role of adenylate kinase and glycolytic enzymes

Por Aksentijević, Dunja, Lygate, Craig A., Makinen, Kimmo, Zervou, Sevasti, Sebag-Montefiore, Liam, Medway, Debra, Barnes, Hannah, Schneider, Jurgen E., Neubauer, Stefan
Publicado em 2010

Unchanged mitochondrial organization and compartmentation of high-energy phosphates in creatine-deficient GAMT(−/−) mouse hearts

Por Branovets, Jelena, Sepp, Mervi, Kotlyarova, Svetlana, Jepihhina, Natalja, Sokolova, Niina, Aksentijevic, Dunja, Lygate, Craig A., Neubauer, Stefan, Vendelin, Marko, Birkedal, Rikke
Publicado em 2013

Chronic creatine kinase deficiency eventually leads to congestive heart failure, but severity is dependent on genetic background, gender and age

Por Lygate, Craig A., Medway, Debra J., Ostrowski, Philip J., Aksentijevic, Dunja, Sebag-Montefiore, Liam, Hunyor, Imre, Zervou, Sevasti, Schneider, Jurgen E., Neubauer, Stefan
Publicado em 2012

Cardiac dysfunction and peri-weaning mortality in malonyl-coenzyme A decarboxylase (MCD) knockout mice as a consequence of restricting substrate plasticity

Por Aksentijević, Dunja, McAndrew, Debra J., Karlstädt, Anja, Zervou, Sevasti, Sebag-Montefiore, Liam, Cross, Rebecca, Douglas, Gillian, Regitz-Zagrosek, Vera, Lopaschuk, Gary D., Neubauer, Stefan, Lygate, Craig A.
Publicado em 2014

Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation

Por Mansor, Latt S., Mehta, Keshavi, Aksentijevic, Dunja, Carr, Carolyn A., Lund, Trine, Cole, Mark A., Page, Lydia Le, Sousa Fialho, Maria da Luz, Shattock, Michael J., Aasum, Ellen, Clarke, Kieran, Tyler, Damian J, Heather, Lisa C.
Publicado no J Physiol (2015)

Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction

Por Lygate, Craig A., Bohl, Steffen, ten Hove, Michiel, Faller, Kiterie M.E., Ostrowski, Philip J., Zervou, Sevasti, Medway, Debra J., Aksentijevic, Dunja, Sebag-Montefiore, Liam, Wallis, Julie, Clarke, Kieran, Watkins, Hugh, Schneider, Jürgen E., Neubauer, Stefan
Publicado em 2012

Living Without Creatine: Unchanged Exercise Capacity and Response to Chronic Myocardial Infarction in Creatine-Deficient Mice

Por Lygate, Craig A., Aksentijevic, Dunja, Dawson, Dana, Hove, Michiel ten, Phillips, Darci, de Bono, Joseph P., Medway, Debra J., Sebag-Montefiore, Liam, Hunyor, Imre, Channon, Keith M., Clarke, Kieran, Zervou, Sevasti, Watkins, Hugh, Balaban, Robert S., Neubauer, Stefan
Publicado em 2013

On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury

Por Cole, Mark A., Abd Jamil, Amira H., Heather, Lisa C., Murray, Andrew J., Sutton, Elizabeth R., Slingo, Mary, Sebag-Montefiore, Liam, Tan, Suat Cheng, Aksentijević, Dunja, Gildea, Ottilie S., Stuckey, Daniel J., Yeoh, Kar Kheng, Carr, Carolyn A., Evans, Rhys D., Aasum, Ellen, Schofield, Christopher J., Ratcliffe, Peter J., Neubauer, Stefan, Robbins, Peter A., Clarke, Kieran
Publicado no FASEB J (2016)

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

Por Chouchani, Edward T., Pell, Victoria R., Gaude, Edoardo, Aksentijević, Dunja, Sundier, Stephanie Y., Robb, Ellen L., Logan, Angela, Nadtochiy, Sergiy M., Ord, Emily N. J., Smith, Anthony C., Eyassu, Filmon, Shirley, Rachel, Hu, Chou-Hui, Dare, Anna J., James, Andrew M., Rogatti, Sebastian, Hartley, Richard C., Eaton, Simon, Costa, Ana S.H., Brookes, Paul S., Davidson, Sean M., Duchen, Michael R., Saeb-Parsy, Kourosh, Shattock, Michael J., Robinson, Alan J., Work, Lorraine M., Frezza, Christian, Krieg, Thomas, Murphy, Michael P.
Publicado no Nature (2014)

Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway

Por Ashrafian, Houman, Czibik, Gabor, Bellahcene, Mohamed, Aksentijević, Dunja, Smith, Anthony C., Mitchell, Sarah J., Dodd, Michael S., Kirwan, Jennifer, Byrne, Jonathan J., Ludwig, Christian, Isackson, Henrik, Yavari, Arash, Støttrup, Nicolaj B., Contractor, Hussain, Cahill, Thomas J., Sahgal, Natasha, Ball, Daniel R., Birkler, Rune I.D., Hargreaves, Iain, Tennant, Daniel A., Land, John, Lygate, Craig A., Johannsen, Mogens, Kharbanda, Rajesh K., Neubauer, Stefan, Redwood, Charles, de Cabo, Rafael, Ahmet, Ismayil, Talan, Mark, Günther, Ulrich L., Robinson, Alan J., Viant, Mark R., Pollard, Patrick J., Tyler, Damian J., Watkins, Hugh
Publicado em 2012