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Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction

AIMS: Increasing energy storage capacity by elevating creatine and phosphocreatine (PCr) levels to increase ATP availability is an attractive concept for protecting against ischaemia and heart failure. However, testing this hypothesis has not been possible since oral creatine supplementation is inef...

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Bibliografiske detaljer
Main Authors: Lygate, Craig A., Bohl, Steffen, ten Hove, Michiel, Faller, Kiterie M.E., Ostrowski, Philip J., Zervou, Sevasti, Medway, Debra J., Aksentijevic, Dunja, Sebag-Montefiore, Liam, Wallis, Julie, Clarke, Kieran, Watkins, Hugh, Schneider, Jürgen E., Neubauer, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500046/
https://ncbi.nlm.nih.gov/pubmed/22915766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs272
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