Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction

AIMS: Increasing energy storage capacity by elevating creatine and phosphocreatine (PCr) levels to increase ATP availability is an attractive concept for protecting against ischaemia and heart failure. However, testing this hypothesis has not been possible since oral creatine supplementation is inef...

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Detalhes bibliográficos
Main Authors: Lygate, Craig A., Bohl, Steffen, ten Hove, Michiel, Faller, Kiterie M.E., Ostrowski, Philip J., Zervou, Sevasti, Medway, Debra J., Aksentijevic, Dunja, Sebag-Montefiore, Liam, Wallis, Julie, Clarke, Kieran, Watkins, Hugh, Schneider, Jürgen E., Neubauer, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500046/
https://ncbi.nlm.nih.gov/pubmed/22915766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs272
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