Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation

Adaptation to hypoxia makes the heart more oxygen efficient, by metabolising more glucose. In contrast, type 2 diabetes makes the heart metabolise more fatty acids. Diabetes increases the chances of the heart being exposed to hypoxia, but whether the diabetic heart can adapt and respond is unknown....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Physiol
Prif Awduron: Mansor, Latt S., Mehta, Keshavi, Aksentijevic, Dunja, Carr, Carolyn A., Lund, Trine, Cole, Mark A., Page, Lydia Le, Sousa Fialho, Maria da Luz, Shattock, Michael J., Aasum, Ellen, Clarke, Kieran, Tyler, Damian J, Heather, Lisa C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2015
Pynciau:
Cardiovascular
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713751/
https://ncbi.nlm.nih.gov/pubmed/26574233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271242
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